Local Fibrinolytic Therapy for Acute Embolic Stroke
نویسندگان
چکیده
منابع مشابه
Fibrinolytic Therapy in Acute Stroke
Acute ischemic stroke is a major cause of morbidity and mortality in Europe, North America, and Asia. Its treatment has completely changed over the past decade with different interventional approaches, such as intravenous trials, intra-arterial trials, combined intravenous/intra-arterial trials, and newer devices to mechanically remove the clot from intracranial arteries. Intravenous thrombolys...
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The possibility that intra-arterial local infusion of fibrinolytic agents may achieve recanalization of previously occluded carotid territory arteries in acute stroke was tested in a prospective angiography-based open pilot study at two centers. Fifteen of 20 patients with acute symptoms (mean treatment-onset interval 7.6 hours) demonstrated complete recanalization; 10 of the 15 patients exhibi...
متن کاملTherapeutic Hypothermia for Acute Air Embolic Stroke
We describe a 65-year-old man who presented to the emergency department with acute cerebral air embolism after receiving computed tomography guided lung biopsy. The patient presented with muscle strengths of 0/5 in left arm and 3/5 in left leg, aphasia, and a right pneumothorax. Our concern was to improve the patient’s neurological function, while ensuring stability in a patient who possibly ha...
متن کاملDelayed combination therapy of local brain hypothermia and decompressive craniectomy on acute stroke outcome in rat
Objective(s):Hypothermia and decompressive craniectomy (DC) have been shown to be neuroprotective. This study was designed to evaluate neuroprotective effects of delayed singular or combination of DC and local hypothermia on stroke. Materials and Methods: Cerebral ischemia was induced in 48 Wistar rats assigned to 4 groups: control, decompressive craniectomy (DC), local hypothermia (LH), combin...
متن کاملEfficacy of recombinant annexin 2 for fibrinolytic therapy in a rat embolic stroke model: a magnetic resonance imaging study.
Efficacy of recombinant annexin 2 (rAN II) in a rat model of embolic stroke was examined using a magnetic resonance imaging (MRI) and histology. The right middle cerebral artery of male Wistar rats was occluded by autologous clots under anesthesia. Four doses of rAN II (0.125, 0.25, 0.5 and 1.0 mg/kg, n=10 for each group) or saline (1 ml/kg, n=10) were administrated intravenously within 5 min b...
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ژورنال
عنوان ژورنال: Surgery for Cerebral Stroke
سال: 1999
ISSN: 0914-5508
DOI: 10.2335/scs1987.27.5_386